PhD project: Within-person evolution of the human microbiome.

The research group of Felix M. Key at the Max Planck Institute for Infection Biology in Berlin is looking to recruit an outstanding student for a project starting in 2023.

Project Description:
The human microbiome describes the entirety of microbes on an individual and its establishment has important implications for human health. The human microbiome contains trillions of microbes, which harbor an enormous adaptive potential, generating millions of new mutations every day. However, we have a very limited understanding about the role of the species-specific genetic variability for colonization and perturbation of the human microbiome throughout life.
Here we will use whole-genome sequencing of cultured bacterial isolates combined with metagenomics from individuals to reconstruct the genetic drivers behind persistent colonization and perturbations during health and disease. A better understanding of the genetic mechanisms provides the basis for the development of new strategies to support the establishment of a healthy human microbiome.
Therefore, we are looking for a motivated student to work at the interface of microbiology (incl. robotic automation) and computational genetics in our lab. The ideal candidate has knowledge in a programming language (python, bash, R etc.) and a background in microbiology, genetics, bioinformatics, evolutionary biology or neighboring disciplines.

We offer:
• outstanding research and training opportunities with access to state-of-the-art facilities
• an excellent scientific network
• a structured graduate school program – students will be registered with the prestigious International Max Planck Research School for Infectious Diseases and Immunology (IMPRS-IDI) with a curriculum adapted to the projects and a strong PhD student community
• a stimulating international and multi-disciplinary research environment on a thriving campus in the heart of Berlin

We are looking for:
– creative and highly motivated Ph.D. students of all nationalities who are strongly committed to research
– candidates with a strong background in bioinformatics, genetics, computer science, microbiology, evolutionary biology or neighboring disciplines
– knowledge in programming (python, bash, R etc.) as well as high-throughput sequencing is strongly desired
– applicants must have an excellent M.Sc. or equivalent degree

Interested in joining us?
To apply, please submit your application via our online application platform https://imprs-app.mpiib-berlin.mpg.de until October 31st 2022.

For more information on the projects and application process, please check the IMPRS-IDI website at:
https://www.mpiib-berlin.mpg.de/2130415/imprs-idi-call-for-applications-2023

Contact: IMPRS-IDI Coordination Office (imprs-office@mpiib-berlin.mpg.de)