Staff Research Associate III

MED-ZSFG-EXPM

Full Time

69842BR

Job Summary

The Rutishauser Lab (https://experimentalmedicine.ucsf.edu/laboratories/rutishauser-lab ) in the Department of Medicine, Division of Experimental Medicine at UCSF based at Zuckerberg San Francisco General Hospital seeks a highly motivated SRA 3 to work as a part-time (85%) research technician and part-time (10%) laboratory manager (for a lab of 5-7 people). The laboratory focuses on understanding the mechanisms that promote the formation of protective immunity to viral pathogens across different stages of human development. The candidate will work on several highly collaborative projects that seek to (1) identify the cell-intrinsic (i.e., transcriptional and epigenetic) and cell-extrinsic (i.e., inflammatory cytokine and tissue environment) regulators of T cell exhaustion in chronic HIV infection, (2) determine whether HIV-specific CD8+ T cell exhaustion can be overcome by immune-based interventions (e.g., therapeutic vaccination), and (3) determine the molecular basis of altered CD8+ T cell effector differentiation in early human life and the consequences for the formation of protective immunity in infants. The successful candidate will ideally show proficiency with various laboratory techniques and computer programs, including experience with and/or interest in developing skills in cellular immunology assays (flow and mass cytometry) and analysis (including basic programming using R). Our laboratory strongly values mentorship and support of technicians in developing independence with experimental design, execution, analysis, and presentation, as well as career development. The lab is based in a research Division devoted to studying the pathogenesis and immunology of human chronic infectious diseases (HIV, TB, malaria).

We’re about creating exceptional experience for our employees. Our goal is to provide opportunities for our diverse employee population to develop and grow careers in a team-oriented environment focused on research. 
Every employee, at every level, begins their career at UCSF learning about the history of the organization and its established culture built on trust and integrity. Our employees drive this culture, and we want you to be a part of it.  

Note: This position requires physical/health screening.

Department Description

The Division of Experimental Medicine is a translational, wet lab research unit comprised of 8 immunological research groups consisting of 10 faculty members and 65+ staff, trainees, and post-docs. Our labs use cutting edge technologies to answer clinically important questions about host-pathogen interactions across globally devastating infectious diseases, including HIV, Malaria, SARS-CoV-2, and Tuberculosis.

Our division aspires to be an actively anti-racist group. We welcome applicants who will contribute to our institution-wide efforts celebrating our cultural backgrounds and be resolute in advancing diversity, equity, inclusion, and anti-racism activities. Visit our website [http://tiny.ucsf.edu/EXPMsalary ] for salary, benefits, and union representation details.

Required Qualifications

• BA/BS in a related science and TWO or more years of recent, directly related work experience, utilizing the techniques or methods required by the position (flow and/or mass cytometry, RNA sequencing); demonstrating technical expertise in these areas; and/or an equivalent combination of experience/training.
• Experience working under Biosafety Level 2 (or above) conditions
• Experience with good sterile technique.
• Proficiency in tissue and cell processing
• Experience staining cells for flow cytometry assays
• Ability to follow written procedures accurately and maintain accurate lab notebook, participant records and specimen inventory
• Strong computer literacy skills, including Word and Excel
• Strong organizational and communication skills

Preferred Qualifications

• M.S./M.A. degree in a biological, chemical or physical science
• Experience working in an immunology laboratory
• Ability to work efficiently within a team environment as well as independently
• Experience with isolation of cells from human blood and tissue specimens by enzymatic digestion, density gradients and magnetic enrichment
• Experience thawing viable cryopreserved cells
• Knowledge of fluorochromes used in flow cytometry
• Experience operating flow cytometers/sorters, particularly BD LSR-II, Aria, or Cytek Aurora
• Experience with R programming for analysis of data generated from cellular or molecular biology assays
• Laboratory management experience

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity – both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Job Code and Payroll Title

009611 SRA 3

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees – Research Support Professionals Unit (UPTE-RX)

Location

Zuckerberg San Francisco General (ZSFG)

Additional Shift Details

Monday – Friday, 9:00am – 5:30pm