Research Fellow – Neurology

Mayo

A post-doctoral position is available immediately in the Department of Neurology at the Mayo Clinic College of Medicine. This one-year renewable position will be focused on preclinical studies of therapeutic efficacy and molecular mechanisms of small molecule mitochondria-targeted therapeutics in mouse models of Alzheimer’s Diseases. The laboratory integrates several disciplines, including mitochondria biology, biochemistry, systems biology approaches including metabolomic and transcriptomic analyses, and has a strong translational focus, with activities in preclinical studies and development of novel therapeutics and biomarkers of efficacy. 

We are seeking a highly motivated individual with a solid background in neuroscience. The successful candidate will be a self-driven scientist, enjoying challenging research projects in a supportive multidisciplinary environment, and working in a timely fashion with team members. Enjoyment of team science is essential, along with strong communication and presentation skills in English. Investigation will be conducted in vivo in mice, iPSC-derived human neurons, multiple tissues and biofluids, and human cells. The in-depth knowledge of in vivo techniques involving mouse models and major in vitro biochemistry techniques are mandatory. Understanding of mitochondrial biology, cellular metabolism and energetics is an advantage. 

Required Qualifications 

    1. Candidates must have a Ph.D. or M.D./Ph.D. degree in Biological Sciences and have at least two-year research experiences in the neuroscience field. 

    2. Proficiency in in vivo techniques involving mouse models including administering drug treatment, conducting behavior studies, collecting tissues and biofluids for analyses including statistical analysis.

    3. Proficiency in immunohistochemistry, imaging techniques including fluorescence and confocal microscopy, and data analysis. 

    4. Basic cell biology techniques including ELISA, SDS-PAGE, western blot, PCR, and other basic assays. 

    5. Proficiency in basic cell culture techniques. Experience with neuronal cultures is an advantage.

The candidate will also be expected to write manuscripts reporting research findings, originate new, related, or follow-up research projects, and to originate/participate in grant proposal writing to support the lab. This opportunity is open to U.S. and non-U.S. residents; position is available immediately.

Applications, including curriculum vitae and bibliography, summary of past accomplishments, and three letters of recommendation, should be submitted together and addressed to:

Eugenia Trushina, PhD

Mayo Clinic 

200 First Street SW

Rochester, MN U.S.A. 55905

Email:  [email protected]

A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic.

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