Research Fellow – Cellular cryo-tomography of mitochondria

Research Fellow – Cellular cryo-tomography of mitochondria

Job No.: 643094

Location: Clayton campus

Employment Type: Full-time

Duration: 2-year fixed-term appointment 

Remuneration: $72,927 – $98,975 pa Level A (plus 17% employer superannuation)

• Be inspired, every day
• Drive your own learning at one of the world’s top 80 universities
• Take your career in exciting, rewarding directions

The Department of Biochemistry & Molecular Biology is the premier Australian Department in its discipline. Its research and teaching aims to understand and communicate biological processes and how these are altered in disease. Research and teaching in the department encompass six broad themes: cell biology, signal transduction, host/pathogen interaction, structural biology, immunology and developmental biology. The research is highly relevant to major human diseases and pathological processes, including infection, inflammation, diabetes and obesity, developmental and degenerative disorders, cardiovascular disease, and cancer.

The Ramaciotti Centre for Cryo-Electron Microscopy is a university research platform and is part of the national grid of Microscopy Australia facilities. Its mission is to enable and advance research excellence through the provision of a world-class research capability in electron microscopy for the biomedical sciences. The Centre enables life sciences EM workflows from experimental design to data analysis with expertise in immuno EM, volume EM, correlative light and electron microscopy, cryo tomography and single particle analysis.

The Opportunity

The research fellow will conduct research and develop research expertise in high-resolution Cryo-EM imaging of mitochondria under stress. This ARC funded position is aimed at characterising the formation and fate of DNA-containing mitochondrial-derived vesicles in apoptotic cells. The project will require expertise in microscopy and cell biology preferably in the area of mitochondrial biology and/or membrane trafficking. A combination of optical microscopy techniques together with Cryo-CLEM, Cryo-FIB-milling and cryo-tomography will be used throughout the project. The position is under the joint supervision of Associate Professor Georg Ramm and Dr Kate McArthur together with Professor Ben Kile at the University of Adelaide.

About you:

To be successful in this role, you will have:

• A doctoral qualification in the relevant discipline (i.e., biochemistry or cell biology) or a closely related field
• Expertise in microscopy and cell biology preferably in the area of mitochondrial biology and/or membrane trafficking
• Demonstrated project management skills with the ability to supervise, mentor and support the development of research staff and postgraduate students

Monash benefits include:

• Hybrid and flexible work arrangements available – Work from home 2 days a week
• Professional development and study support
• Collaborative and Inclusive culture
• Health and well-being initiatives – Employee Assistance Program (provided by Benestar) available to all employees and their immediate family members
• Salary packaging options available and staff discounts

This role is a full-time position; however, flexible working arrangements may be negotiated.

For instructions on how to apply, please refer to “How to apply for Monash Jobs ”.

We encourage applications from First Nations people, culturally and linguistically diverse people, people with disabilities, neurodiverse people, and people of all genders, sexualities and age groups.

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Enquiries

Associate Professor Georg Ramm, Ramaciotti Centre for Cryo-EM & Department of Biochemistry and Molecular Biology, +61 3 9905 1280

Position Description

 Research Fellow – Cellular cryo-tomography of mitochondria

Closing Date

Sunday 27 November 2022, 11:55pm AEDT

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