Research Associate* – Microbiology

Job title:

Research Associate* – Microbiology

Company

Moglichkeiten Arbeitgeber

Job description

As a part of our team of more than 5.000 pioneers, you will play a key role in developing solutions for some of the most crucial scientific challenges of our age. Within less than a year, we were able to develop our COVID-19 mRNA vaccine following the highest scientific and ethical standards – writing medical history.BioNTech R&D Austria is a wholly owned subsidiary of BioNTech SE, focused on the development of novel antibacterial drugs to treat persistent bacterial infections. Our development programs are based on our proprietary LysinBuilder platform, which allows the targeted development of synthetic lysins for virtually any bacterial pathogen. We use a combination of randomized directed evolution approaches and rational in-silico engineering, coupled to high-throughput screening, to generate artificial lysins and develop them into drugs. The development pipeline focuses on chronic bacterial infections where antibiotics fail to cure or destroy the natural microbiomes. Our lead asset is BNT331, which we develop for the treatment of bacterial vaginosis. We also work on transforming the standard of care with lysins against several other infections and dysbioses.Research Associate* – MicrobiologyAs Research Associate* at BioNTech R&D Austria you will join our research team and help us bring next generation drugs from the bench into the clinic.Your main responsibilities are:Within the scope of your assignment, autonomously execute series of experiments to support the developmental program, all following established protocols and in accordance with general guidelines and instructions, including:

• Activity testing of lysins against bacterial strains (BSL-2 strains like Gardnerella, others)
• Biofilm assays
• Isolation of bacteria from human and environmental samples
• Characterization of endolysins (e.g. MIC, lysis kinetic, surface staining)
• Analysis of ex vivo samples (e.g. PK measurements by ELISA, qPCR)

Actively participate in designing the required experiments and improving the established protocols, as part of the lab teamIf necessary, develop capabilities in operating advanced equipment, including programming of a pipetting robot and flow cytometer as well as documentation methodsDocumentation of results according to the internal quality standards (near-GLP), to ensure the quality of the documentation meets the expectation of the authorities regarding a marketing authorization for a pharmaceuticalMaintain laboratory infrastructure, including purchasing of reagents and equipment, and constantly making materials like media and agar plates available, documenting and maintaining the inventory of biological materialsWhat you have to Offer:Completed university degree (BSc. or MSc.) in microbiology, infection biology or a related subject or vocational training as lab technician (this position is not suitable for candidates with a PhD)At least 1 year of (cumulative) laboratory experience during internships or work experience. Extensive laboratory or biotech experience is a plus and will be reflected in the compensation package

At least 6 months research experience in at least one of the following areas:Microbiological assays (biofilms, MIC assays, killing assays, etc.), preferably involving proteinsELISA, Flow cytometry, Microscopy, qPCRDetection, isolation and typing of bacteria from human samplesInterest in targeted pharmaceutical development and working in a team of highly skilled and motivated professionalsFluent in EnglishBenefits for you:Become part of developing a new drug class in anti-infectivesTake responsibility for specific parts of the development program and work together with highly experienced researchers in executing the development planPioneer new methods and processes to industrialize key research techniquesBe part of a highly motivated, multinational and fun team that believes synthetic lysins can be part of the solution to the global antibiotics crisisA competitive compensation package that reflects the qualifications and seniority of the candidate and may include further, e.g. performance-based, incentivesDue to legal requirements, we are obliged to state that the minimum salary for this job is based on the applicable collective bargaining agreement and will be determined based on the work experience of the candidate at this job level. For this job the job level is expected to be at III and the corresponding range of minimum salary is from €2.369,18 gross per month (with no prior experience at this work level) to €3.597,62 (for a candidate with more than 15 years prior experience at this work level). Please note that the total remuneration (minimum salary plus potential overpayment plus potential additional salary components) will be market oriented and in line with the experience and qualifications of the successful candidate.Have we kindled your pioneering spirit?Then apply now for our location Austria/Wien and simply send us your application documents using our online form.If you have any further questions, our Talent Acquisition Team will be happy to answer them on + 49 (0) 6131-9084-1291 (monday-friday, from 12 noon to 4 pm). Job-ID 7082 (please indicate for inquiries) We look forward to your application! *BioNTech does not tolerate discrimination, favoritism, or harassment based on gender, political opinion, religion or belief, nationality, ethnic or social origin, age, sexual orientation, marital status, disability, physical appearance, health status or any other aspect of personal status. We are committed to creating a diverse and inclusive environment and are proud to be an equal opportunity employer. Most important – it’s a match!

Expected salary

€2369.18 per month

Location

Wien

Job date

Sun, 07 Apr 2024 02:28:06 GMT

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