Research Associate in Quantitative Synthetic Biology

Imperial College London

Job description
Job summary

We are looking for a Postdoctoral Researcher to join the synthetic biology research group of Professor Tom Ellis in the Department of Bioengineering, Imperial College London.

Duties and responsibilities

This Research Associate role is funded by the BBSRC and is a one-year mini project to provide data to complement a larger UK-USA project on developing the fundamentals of synthetic cell-like systems. This work package of the project requires the research associate to gather new data on the relationship between nuclear volume and effective DNA site concentrations and efficiency in transcription and regulation. This will require using vesicle cell mimics with bacteria lysates and/or commercial reactions to assess repetitive DNA elements and transcriptional units at different copy numbers. DNA cloning of repetitive constructs of different designs will be a key part of project, along with measurements using microscopy, microfluidics and fluorescence quantification. Mathematical analysis of the data will be required, along with work with our collaborators in chemical biology and control theory.

Essential requirements

Due to the short nature of the funding for this role, it is essential that the applicant have demonstrated existing expertise in synthetic biology and cloning repetitive DNA elements and have a track record of working on collaborative projects that span both biology and chemistry.

Applicants must have a PhD in synthetic biology for appointment at Research Associate level. Applicants close to completion of their PhDs will also be considered where experience is directly relevant.

Please see the job description and person specification document associated with this advert for the full list of criteria.

Further information

This is afull time, fixed-term appointment for 12 months.

*Candidates who have not yet been officially awarded their PhD will be appointed as Research Assistant within the salary range £38,194 – £41,388 per annum.

If you have any queries about this role please contact: Professor Tom Ellis at [email protected]

Our preferred method of application is via our website. Please click “APPLY NOW” to go through to the online application form. Should you have any queries regarding the application process please contact: Yusra Vallimohamed at [email protected]

For technical issues when applying online please email [email protected] Please ensure that you include the job reference number in any correspondence.

The Department of Bioengineering leads the bioengineering agenda both nationally and internationally, with its staff coming from diverse academic disciplines, including all main branches of engineering, physical sciences, life sciences and medicine, to create a rich collaborative environment. More information about staff benefits, including generous annual leave entitlements and excellent professional development opportunities, can be found here:

Committed to equality and valuing diversity. We are also an Athena SWAN Silver Award winner, a Stonewall Diversity Champion, a Disability Confident Employer, and are working in partnership with GIRES to promote respect for trans people


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