Postdoctoral Training Fellow in Computational Biology – Fröhlich lab

Postdoctoral Training Fellow in Computational Biology – Fröhlich lab

Reporting to: Fabian Fröhlich, Group Leader

Contact term: This is a full-time, fixed term (4 years) position on Crick terms and conditions of employment

The Research Group
The Fröhlich lab develops models to describe the dynamic behaviour of biological systems combining techniques from mathematical modelling and machine learning. We develop computational tools to build and train these models on experimental data and apply these tools to understand the regulatory principles that determine the dynamic response to external perturbations. More details about the group and our research interests can be found here: www.frohlichlab.com

The successful candidate will join a growing, multi-disciplinary team of scientists with the opportunity to contribute own ideas and help shape the research profile of the lab. Research projects will be supported by a vibrant, multi-disciplinary scientific community at the Crick, with ample opportunities for internal and external collaborations. Moreover, the candidate will have access to state-of-the-art core facilities at the Crick, including the High-Performance-Computing platform, and rich structured career development and networking opportunities.

The Role
Several research directions are being pursued and the successful candidate will have the freedom to develop and undertake their own independent research projects within the scope of the lab’s interests. Topics include development of hybrid models that use machine learning methods to contextualize ordinary differential equation (ODE) models using (single-cell) omics and imaging data; and the development of neural-network-based coarse-graining of protein-structure-based models.

The post holder will be responsible for:

Leading and developing specific research projects
Developing and maintaining computational tools for the contextualization of ODE models
Applying methods to biological data and interpreting results
Collaborating with national and international partners
Presenting work at lab meetings as well as national and international meetings
Publishing scientific results
Assisting in training graduate students and other members of the laboratory
Key experience and competencies
The post holder should embody and demonstrate our core Crick values:

Bold; Open; Collegial, in addition to the following:

Essential
PhD in a relevant field or in the final stages of PhD submission
Good knowledge and experience in coding (Python/Julia/C or similar languages), mathematics and statistics
Technical expertise in either mathematical modelling or machine learning
An interest in applying computational methods to biological problems
A demonstrated ability to generate and pursue independent research ideas
Excellent communication skills, written and verbal as evidenced by publications, preprints and conference presentations
Cross-disciplinary mindset, collaborative attitude and teamwork experience
Dedication to reproducible research and open science
Desirable
Experience with high-performance computing
Experience with ordinary differential equation models
Experience with dimensionality reduction and deep learning methods
Experience with working in interdisciplinary environments
Experience in developing and maintaining scientific software
About Us
At the Crick, we conduct research at the forefront of biomedical research. We combine rigour with an open and collaborative culture, and are outward-looking, reflecting our status as a partnership of six organisations aiming to pool knowledge, ideas and resources.

We have a wide research portfolio with no divisions or departments, bringing biomedical researchers together with clinicians, physical scientists and applied scientists from our pharmaceutical partners.

We aim to attract the most talented researchers and support them to tackle innovative research questions. Our science technology platforms provide our researchers with access to state-of-the-art technology and expertise.

We provide an excellent learning environment with dedicated education programmes in public engagement with science, education and personal development, and a postdoc training programme that prepares scientists for leadership roles in science.

If you are interested in applying for this role, please apply via our website.
The closing date for applications is 30/11/2022 at 23:59 GMT
All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.
If you require a visa to work in the UK we will help support your application should you be successful
Find out what benefits the Crick has to offer:

For more information on our great pay and benefits package please click here: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/pay-and-benefits

Equality, Diversity & Inclusion:

We welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status. We particularly welcome applications from people who are Minority Ethnic as they are currently underrepresented in the Crick at this level.

Diversity is essential to excellence in scientific endeavour. It increases breadth and perspective, leading to more innovation and creativity. We want the Crick to be a place where everyone feels valued and where diversity is celebrated and seen as part of the foundation for our Institute’s success.

The Crick is committed to creating equality of opportunity and promoting diversity and inclusivity. We all share in the responsibility to actively promote dignity, respect, inclusivity and equal treatment and it is our aim to ensure that these principles are reflected and implemented in all strategies, policies and practices.

Read more on our website: https://www.crick.ac.uk/careers-and-study/life-at-the-crick/equality-diversity-and-inclusion