POSTDOCTORAL SCHOLAR

A postdoctoral position is immediately available in the Department of Pathology, University of Iowa Carver College of Medicine. Our laboratory utilizes a genetically modified mouse models and human induced pluripotent stem cells to model human diseases, focusing on understanding of mitochondrial / metabolic signaling and function in various diseases and in aging, in order to develop interventions to delay aging or to treat human diseases. Currently we are working on cardiomyopathy / heart failure, cardiac arrhythmia, cardiac and kidney aging, myeloma-associated kidney diseases, polycystic kidney diseases and mitochondrial encephalo-cardiomyopathy. Our projects use genetically modified mouse models and cardiomyocytes / neuronal cells /organoid derived from human induced pluripotent stem cells. Applicants should have a strong background in molecular and cellular biology and experience with genetic mouse models. The selected candidate will be expected to work independently while interacting in a collaborative environment.

PhD, MD/PhD or MD with significant bench research experience.

Good communication and writing skills in English.

Experience working with mice.

Experience with general protein analysis and immunostaining.

Experience in developing and analyzing genetic mouse models, CRISPR/Cas technology, stem cell culture, in vitro cardiomyocyte / neuronal studies, mouse survival surgery, Langendorff hanging heart system, electrophysiology.

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