Postdoctoral Researcher – Image Analysis and Advanced Fluorescence Microscopy

Centre for Genomic Regulation

18 Oct 2023
Job Information

Centre for Genomic Regulation
Research Field
Biological sciences » Biology
Researcher Profile
Recognised Researcher (R2)
Established Researcher (R3)
Application Deadline
10 Nov 2023 – 00:00 (Europe/Madrid)
Type of Contract
Job Status
Hours Per Week
Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

Offer Description

The Institute


The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.

In April 2021, the Centre for Genomic Regulation (CRG) received the renewal of the ‘HR Excellence in Research ‘ Award from the European Commission. This is a recognition of the Institute’s commitment to developing an HR Strategy for Researchers, designed to bring the practices and procedures in line with the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers (Charter and Code).


Please, check out our Recruitment Policy


The role


The position is expected to be filled by a PhD-level candidate with experience in bioimage analysis and advanced fluorescence microscopy. The candidate will focus on the development of computational tools for the analysis of live cell fluorescence microscopy data from multi-model data types. A focus is placed on the analysis of cell and tissue morphodynamics and spatio-temporal feature extraction at the single cell level based on in vivo and in vitro microscopy data.


The candidate should be enthusiastic to work in a collaborative and interdisciplinary research environment. This work will be performed within the European Synergy Grant ‘Breakdance’ that involves 4 European research partners in Spain and France.

About the lab


The Ruprecht lab studies fundamental mechanisms regulating cellular morphodynamics, tissue plasticity and multicellular self-organization during development and disease conditions. The team employs a cross-disciplinary approach that combines quantitative fluorescence microscopy, biophysical methods, synthetic biology approaches and in vivo model systems. Our work has recently identified that nuclear mechanosensing controls cellular mechano-plasticity (Venturini et al. Science 2020) and has elucidated mechanisms of developmental robustness via cellular error correction in the early embryo (Hoijman et al. Nature 2020). Our ultimate goal is to develop a mechanistic understanding how tissue form and function is robustly built and maintained by dynamic processes at the single cell level and of alterations of cell states in disease and ageing.

The research group is part of the Quantitative Cell Biology Program and Systems and Synthetic Biology Program at the CRG.


Whom would we like to hire?


Professional experience

Must Have

  • You have expertise in bioimage analysis and advanced fluorescence microscopy methods
  • You have developed computational tools for image processing and analysis
  • You have worked with AI-based imaging methods


Education and training

  • You hold a PhD degree in physics, mathematics, informatics or a related field with relevant qualifications


  • You are fluent in English, and you have excellent communication and writing skills



  • You are a highly motivated person with analytical problem-solving skills
  • You bring an excellent scientific track record
  • You are enthusiastic to work in a collaborative and interdisciplinary research team


Technical skills

  • You have worked with 2D, 3D and 4D live cell fluorescence microscopy data
  • You have experience in handling multi-modal imaging data (widefield, confocal, light sheet microscopy)
  • You have gained practical skills in AI-based image analysis methods
  • You bring experience in different programming languages (Matlab, Phyton, Fiji, and similar)
  • You are proficient in statistical data analysis
  • You are knowledgeable in cell and developmental biology


The Offer – Working Conditions

    • Contract duration: Technical and scientific activities contract – estimated project duration one year with the possibility to extend
    • Estimated annual gross salary: Salary is commensurate with qualifications and consistent with our pay scales.
    • Target start date: From November 2023


We provide a highly stimulating environment with state-of-the-art infrastructures, and unique professional career development opportunities. To check out our training and development portfolio, please visit our website in the training section .

We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

The CRG is committed to reconcile a work and family life of its employees and are offering extended vacation period and the possibility to benefit from flexible working hours.

Application Procedure

All applications must include:

  • A motivation letter addressed to Dr Verena Ruprecht.
  • A complete CV including contact details.
  • Contact details of two referees.

    All applications must be addressed to Dr. Verena Ruprecht and be submitted online on the CRG Career site –



    Selection Process

    • Pre-selection: The pre-selection process will be based on qualifications and expertise reflected on the candidates CVS. It will be merit-based.


    • Interview: Preselected candidates will be interviewed by the Hiring Manager of the position and a selection panel if required.


    • Offer Letter: Once the successful candidate is identified the People department will send a Job Offer, specifying the start day, salary, working conditions, among other important details.



    Deadline: Please submit your application by November 10th, 2023.




    Suggestions: The CRG believes in ongoing improvement and promotes a culture of feedback. This is one of the reasons we have in place, at your disposal as a candidate, a mechanism to gather your suggestions/complaints concerning your candidate experience in our recruitment processes. Your feedback really matters to us in our aim at creating a positive candidate journey. You can make a difference and help us improve by letting us know your suggestions through the following form .













    Research Field
    Biological sciences » Biology
    Education Level
    PhD or equivalent


    Additional Information
    Work Location(s)

    Number of offers available
    Centre for Genomic Regulation (CRG)
    Postal Code
    Dr. Aiguader, 88

    Where to apply



    C Dr. Aiguader 88
    Postal Code
    [email protected]


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