Postdoctoral Research Associate – Oncology

Job Description

Position Summary

A postdoctoral position is open immediately in the laboratory of Dr. Matthew Walter at Washington University School of Medicine in the Division of Oncology and Section of Stem Cell Biology. Research opportunities are available for highly motivated individuals to join our interdisciplinary team studying blood cancers and the role of spliceosome gene mutations in the initiation and progression of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). We combine in vivo, ex vivo, and in vitro methods to study pathogenic mechanisms. Ongoing projects are focused on understanding the mechanisms driving clonal hematopoiesis and the expansion of mutant cells in MDS and AML. Research approaches will include but not limited to the generation and use of novel mouse models of disease, hematopoietic stem cell assays, tumor biology, and next-generation DNA and RNA sequencing (including whole genome sequencing and single-cell RNA sequencing). Results from preclinical models are validated using the available large bank of primary patient samples and translated into ongoing clinical trials. The postdoctoral fellow will participate and lead research projects to address questions that are both fundamental in biology and highly relevant in the clinic.

Further information about our research can be found at: https://oncology.wustl.edu/people/faculty/Walter/Walter_Res.html .

Primary Duties & Responsibilities

Trains under the supervision of a faculty mentor, including (but not limited to):

• Manages their own project, which should lead to a first author publication.
• Develops proficiency in their chosen scientific discipline/field.
• Develops proficiency in their technical skills.
• Develops proficiency in their ancillary skills, e.g. writing, public speaking, networking, critical evaluation of scientific documents, etc.
• Presents scientific work both inside and outside the University.
• Assists with grant preparation and reporting.
• Prepares and submits papers on research.
• Assists in the design of research experiments.
• Evaluates research findings and assists in the reporting of the results.
• Maintains conscientious discharge of their research responsibilities.
• Maintains conformity with ethical standards in research.
• Maintains compliance with good laboratory practice, including the maintenance of adequate research records
• Engages in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
• Maintains collegial conduct towards co-trainees, staff members and members of the research group.
• Adheres to all applicable University policies, procedures and regulations.  All data, research records and materials and other intellectual property generated in University laboratories remain the property of the University.

Required Qualifications

• Ph.D., M.D. or equivalent terminal or doctoral degree.
• Experience in molecular biology, cancer biology, genetics or a related area.

Preferred Qualifications

Demonstrated ability to implement laboratory procedures, conduct research and records findings.

Working Conditions

This position works in a laboratory environment with potential exposure to biological and chemical hazards.  The individual must be physically able to wear protective equipment.

Salary Range

Base pay is commensurate with experience.

Applicant Special Instructions

Please submit an application electronically with a curriculum vitae, cover letter with a brief description of research experience, and the names/phone number/emails of three references to:

Dr. Matthew Walter

Division of Oncology

Washington University School of Medicine

St. Louis, Missouri, 63110

Email: [email protected]

Accommodation

If you are unable to use our online application system and would like an accommodation, please email [email protected]  or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.

EEO/AA Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

Diversity Statement
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.