Postdoctoral Fellowship in the Division of Cardiology

The Mesubi lab at The Johns Hopkins School of Medicine, Division of Cardiology is actively seeking to recruit a highly motivated postdoctoral fellow to join our lab. Research in our lab is currently focused on understanding the role of the posttranslational modification – O-GlcNAcylation in atrial fibrillation. Our goal is to understand novel fundamental mechanisms of atrial fibrillation and translate this knowledge into development of new therapies for atrial fibrillation. Research in our lab encompasses O-GlcNAc biology, CaMKII biology, intracellular calcium signaling, mitochondrial energetics, atrial fibrillation, and diabetes.

Postdoctoral research fellows will be part of a rich and collegial scientific research community at Johns Hopkins University with access to state-of-the-art research facilities and numerous opportunities for collaboration across the Hopkins campus. Salary and fringe benefits will be compliant with guidelines established by the Johns Hopkins University School of Medicine.

Requirements

• The postdoctoral fellow will work on basic cellular electrophysiology and mouse electrophysiologic studies.
• Glycobiology, OGlcNAc biochemical assays, cloning, expression and purification of proteins, cell culture, enzyme activity assays.
• Cardiac metabolism and mitochondrial energetics.
• Generation of genetic mouse models, and gene editing (e.g. CRISPR, shRNA).
• Ryanodine receptor type 2 (RyR2) and CaMKII biology, protein immunoprecipitation.
• Application of omics technologies – transcriptomics, proteomics and metabolomics.

Qualifications

• Highly motivated candidates with a PhD or MD, or other equivalent doctoral degree in biomedical sciences or biomedical engineering and experience in basic cellular electrophysiology, biochemistry or molecular biology are encouraged to apply.
• Experience and/or expertise in basic cellular electrophysiology and intracellular calcium dynamics is preferred.
• Skills in biochemistry, mitochondrial biology, mouse work, gene manipulation, immunoprecipitation, cell culturing techniques/protein expression are highly desirable.
• Strong analytical skills.
• Candidate should have excellent writing and communication skills, able to work independently but also effectively with other lab members.

To learn more and apply, please send

• A Cover Letter or short statement of research goals
• Curriculum vitae
• 2 3 letters references to Olurotimi Mesubi, MBBS, MPH @ olurotimi.mesubi@jhmi.edu