Post Doc Fellow, Biochemistry Division, Chemistry, Grillo Lab

Current UC employees must apply internally via SuccessFactors > http://bit.ly/UCEMPL

Founded in 1819, the University of Cincinnati ranks among the nation’s best urban public research universities. Home to more than 47,000 students, 10,500 faculty and staff and 330,000 alumni, UC combines a Top 35 research university with a physical setting The New York Times calls “the most ambitious campus design program in the country.”

With the launch of Next Lives Here, the Cincinnati Innovation District, a $100 million JobsOhio investment, eight straight years of record enrollment, worldwide leadership in cooperative education, a dynamic academic health center and entry into the Big 12 athletic conference, UC’s momentum has never been stronger. UC’s annual budget tops $1.6 billion and its endowment totals $1.9 billion.

Job Overview

The Grillo Lab (www.grillolabuc.com) is seeking candidates to join our vibrant team in a full-time position as a Postdoctoral Fellow. Research in the Grillo Lab focuses on the molecular understanding of how genetic, age-related, or environmental-induced mitochondrial dysfunction alters metabolism in neurologic disease. Our research at the interface of biochemistry, metabolism, and physiology employs multiple in vitro and in vivo models to investigate the basic biochemistry and molecular mechanisms of inborn errors of metabolism (e.g. branched chain amino acid deficiencies) and age-progressive neurodegenerative diseases (e.g. tauopathies).

Candidates with a strong background in mitochondrial metabolism, biochemistry, cell biology, aging, hypoxia, mTOR, or metal biology in neurodegenerative diseases are especially encouraged to apply. The postdoctoral scientist will perform laboratory experiments on an independent project under the supervision of Dr. Grillo while assisting other laboratory personnel. The target start date is before October 1st, although timing can be flexible.

Essential Functions

• Independently perform research experiments on an independent project and properly record data according to research protocols under the mentorship of Dr. Grillo.
• Troubleshoot experimental protocols, organize complex data, and analyze/interpret results within the context of the overarching research project.
• Read, analyze, evaluate, and critique primary research to enhance expertise.
• Actively help and/or train other laboratory personnel including postdoctoral scientists, graduate students, and undergraduate students based on professional training or functional experience.
• Establish and manage collaborations between diverse research laboratories.
• Effectively communicate experimental hypotheses, protocols, analyses, results, and project details in one-on-one or group meetings, journal clubs, conferences, etc.
• Actively participate in the writing of research papers, grants, and other documents.
• Attend scientific conferences, meetings, and workshops to enhance the career development of the candidate.
• Apply for extramural funding and training opportunities.
• Mentor junior trainees to enhance their career development.
• Demonstrate continual success in performing increasingly complex experiments or projects that require improved technical skills.
• Perform related duties based on laboratory needs. This job description may change as the research project pro.

Required Education

Ph.D. in biochemistry, cell biology, physiology, chemical biology, neuroscience, or other health-related discipline at the time of appointment.

Additional Qualifications Considered

• Strong record of research accomplishments and peer-reviewed publications.
• Demonstrated oral and written communication skills through previous publications and conference presentations.
• Presentations of scientific results at national meetings.
• Expertise in mitochondrial metabolism, hypoxia, mTOR, and/or metals in age-related neurodegenerative diseases.
• Experience working with mouse models of human disease.
• Experience in isolating primary neurons, cell culture, and aseptic technique.
• Previous work with iPSC-derived neurons.

Physical Requirements/Work Environment

• Sitting – Continuously

Application Process

Applicants must upload the following materials as a single document:

• Cover Letter accepted.
• CV
• A research statement highlighting previous research and impact (1-2 pages)
• A short statement of long-term research interests and goals (<1 page)
• May add up to three relevant publications
• Confidential letter(s) of recommendation sent to Dr. Grillo (grilloas@ucmail.uc.edu) from recommender(s). A maximum of three will be accepted.

Compensation and Benefits

UC offers a wide array of complementary and affordable benefit options, to meet the financial, educational, health, and wellness needs of you and your family. Eligibility varies by position and FTE.

• Competitive salary range dependent on the candidate’s experience.
• Comprehensive insurance plans including medical, dental, vision, and prescription coverage.
• Flexible spending accounts and an award-winning employee wellness program, plus an employee assistance program.
• Financial security via our life and long-term disability insurance, accident and illness insurance, and retirement savings plans.
• Generous paid time off work options including vacation, sick leave, annual holidays, and winter season days in addition to paid parental leave.
• Tuition remission is available for employees and their eligible dependents.
• Enjoy discounts for on and off-campus activities and services.

The University of Cincinnati, as a multi-national and culturally diverse university, is committed to providing an inclusive, equitable and diverse place of learning and employment. As part of a complete job application you will be asked to include a Contribution to Diversity and Inclusion statement.

As a UC employee, and an employee of an Ohio public institution, if hired you will not contribute to the federal Social Security system, other than contributions to Medicare. Instead, UC employees have the option to contribute to a state retirement plan (OPERS, STRS) or an alternative retirement plan (ARP).

The University of Cincinnati is an Affirmative Action / Equal Opportunity Employer / Minority / Female / Disability / Veteran.

REQ: 88102 

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