Offer Description
Takotsubo- or the Broken-Heart syndrome is often triggered by an episode of severe stress followed by acute heart failure in the absence of coronary obstruction, which may also occur in the so- called Stroke-heart syndrome early after stroke. Both cause significant mortality and lack a specific therapy. They also share other aspects, including brain regions typically affected, high levels of stress hormones, and myocardial inflammation (e. g. Nature cardiovascular research 2, 645–655, 2023). We propose that both syndromes are driven by an overlapping pathophysiology and will compare the functional and molecular features of both syndromes with mechanistic dissection including murine cardiac single-cell sequencing and cell culture studies with our cooperation partners (MDC Berlin, Charité Berlin). We are looking for a highly motivated PhD candidate starting May 2024.
Requirements
Skills/Qualifications
1. University degree (master) in Biochemistry, biology, human biology, biomedicine, molecular biology, neuroscience, veterinary medicine
2. Excellent written and spoken English skills (German skills are optimal, but not required)
3. Independent and reliable way of working, outstanding communication skills and team spirit
4. High level of commitment, flexibility, and strong sense of responsibility
5. Experimental experience with small or large animal models is an asset
Additional Information
Selection process
Please submit your application through the HBIGS application system:
https://www.hbigs.uni-heidelberg.de/main_application.html
Additional comments
Please read more under “Open PhD Positions” on: https://www.hbigs.uni-heidelberg.de
Work Location(s)
Where to apply
Contact
STATUS: EXPIRED
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