PhD in molecular oncology (f/m/d)

At the UKE, we are convinced that successful and fulfilling work should be harmonised with the personal needs and individual life plans of all employees. Together we can make this possible.

Every day a little more. Every day a little better.

What to expect

We are the UKE – the University Medical Centre Hamburg-Eppendorf [Universitätsklinikum Hamburg-Eppendorf]. A pulsating centre of health in the heart of Hamburg. When you are surrounded by that much energy and when progress sets the pace, no two days are the same. More than 14,400 employees with very different responsibilities are united by the same goal: ensuring health and well-being.

The UKE offers the opportunity to perform cutting-edge research within an excellent research environment. The junior research group of Dr. Johann von Felden focusses on translational research projects in the field of oncology, with the main objective to derive molecular biomarkers for implementing personalized cancer care for patients with liver cancer. We aim at deciphering mechanisms of hepatocarcinogenesis and identifying biomarkers to predict the response to therapies or improve early cancer detection. We utilize state-of-the-art technologies and modern analytical pipelines, incl. gene editing, murine liver cancer models, next-generation sequencing, and liquid biopsy approaches.

• To continue our established biobank
• To plan and execute experiments, including the establishment of novel protocols and techniques incl.

  o to work with mouse liver cancer models

  o gene transfer with lentiviral vectors in cell culture and organoid models

  o gene expression analysis (e.g. PCR)

  o functional analysis incl. proliferation and migration assays

  o cell sorting and FACS

• General and administrative tasks in the laboratory

This position is temporary for 3 years (65% of regular working hours.)

What we look forward to

• Academic degree in molecular life sciences, biology, bviocehmistry, immunology or related field
• Previous research experience, particularly in the above mentioned techniques, would be preferred.
• Previous experience in the field of oncology is preferred.
• Good knowledge in English, both written and spoken.
• Very good experience in MS Office; previous experience with data analysis, e.g. R is preferred.
• Thorough and structured attitude, solution-oriented.
• Ability to work in a team.
• Eager to learn, readiness of mind.

What we can offer

• Regular pay according to TVöD/VKA; attractive company pension plan and various employee discounts
• 30 days of vacation; possibility of special leave
• Central location: Our clinic is centrally located at the beautiful Eppendorfer Park
• Sustainable travel: subsidies for the HVV-ProfiTicket and Dr. Bike bicycle service; option to lease a service bike
• Crisis-proof workplace, meaningful activity, appreciative interaction and open exchange of knowledge within the team; structured induction training
• Opportunity to actively shape and develop the working environment within the framework of our employee program (UKE INside).
• Family-friendly working environment: cooperation on childcare, free vacation care, advice for employees with relatives in need of care
• Excellent health, prevention and sports offers
• Healthy and varied lunch break: In addition to our canteen, there is a rich selection of culinary offerings just a few steps away, for example the “Health Kitchen” cafés and bistros, as well as other snack bars, bakers, a supermarket, etc.